Chymase Polyclonal Antibody

CMA1 encodes a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and is thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Alternative splicing results in multiple variants.

The Cks2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cks2 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cks2 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The Cks2 protein is a member of the cyclin-dependent kinase (CDK) regulatory subunit family and plays a crucial role in cell cycle progression. Aberrant expression of Cks2 has been implicated in various human cancers, making it an important target for cancer research. The Cks2 Polyclonal Antibody is an essential tool for studying the expression and function of Cks2 in cancer and other diseases.

This antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for its specificity and sensitivity in detecting Cks2 protein in human, mouse, and rat samples. The Cks2 Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

In summary, the Cks2 Polyclonal Antibody is a reliable and high-quality antibody that is essential for studying the expression and function of Cks2 protein in various biological samples. Its specificity and sensitivity make it an ideal tool for cancer research and other related fields.