cGKII Polyclonal Antibody

PRKG2 encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein (protein kinase, cGMP-dependent, type II) plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants.

The cGKII Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of cGKII protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human cGKII protein. The resulting polyclonal antibody exhibits high affinity and specificity towards cGKII protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The cGKII Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its specificity and sensitivity. It recognizes a single band of approximately 85 kDa in Western blot analysis of various tissues and cell lines, and shows minimal cross-reactivity with other related proteins. This antibody is also suitable for use in immunohistochemistry and immunofluorescence, where it can be used to detect cGKII protein in tissue sections and cultured cells.

In summary, the cGKII Polyclonal Antibody is a reliable and high-quality antibody that can be used for the detection of cGKII protein in various biological samples. Its high specificity and sensitivity make it an ideal tool for researchers studying the role of cGKII in various physiological and pathological processes.