Centrobin Polyclonal Antibody

CNTROB encodes a centrosomal protein (centrobin, centriole duplication and spindle assembly protein) that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for CNTROB.

The Cdc16 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cdc16 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdc16 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Cdc16 protein is a key component of the anaphase-promoting complex/cyclosome (APC/C), which is a large multi-subunit E3 ubiquitin ligase that plays a critical role in regulating the cell cycle. Specifically, Cdc16 is involved in the activation of the APC/C during mitosis, which leads to the degradation of key cell cycle regulators and the progression of the cell cycle. Dysregulation of the APC/C has been implicated in a variety of human diseases, including cancer, making the Cdc16 Polyclonal Antibody a valuable tool for researchers studying the molecular mechanisms underlying these diseases.

Overall, the Cdc16 Polyclonal Antibody is a high-quality research reagent that offers excellent sensitivity and specificity for the detection of Cdc16 protein in a variety of biological samples. Its use in a range of applications makes it a versatile tool for researchers studying the cell cycle and related processes.