Centriolin Polyclonal Antibody

Cytokinesis occurs during the late stages of mitosis and describes the process by which the cytoplasm of one cell is divided to create two subsequent daughter cells. Centriolin, also known as CEP110, is a coiled-coil centrosomal protein that is required for centrosome maturation and correct centrosome function. During abscission, the last step in cytokinesis, Centriolin both coordinates and grounds vesicle-fusion and vesicle-exocyst complexes to the midbody of the daughter cells. Acting as an anchor for the protein complexes needed to complete separation of the two cells, Centriolin initiates and controls vesicle-mediated cell cleavage. Through its ability to signal initiation of the last step of vertebrate cytokinesis, Centriolin regulates cell proliferation and contributes to proper entry into the S phase of mitosis.

The Centriolin Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of centriolin protein in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional sensitivity and specificity.

Centriolin, also known as CEP110, is a key component of the centrosome, a vital organelle involved in cell division and organization of the microtubule network. Dysregulation of centriolin has been implicated in various diseases, including cancer and developmental disorders. Therefore, the accurate detection and quantification of centriolin protein levels are of utmost importance in understanding its functional role and potential therapeutic implications.

The Centriolin Polyclonal Antibody exhibits outstanding performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both endogenous and recombinant centriolin protein with high affinity, enabling precise and reliable quantification. This antibody has been extensively validated in multiple cell lines and tissues, ensuring its consistent and reproducible results.

With its exceptional specificity and sensitivity, the Centriolin Polyclonal Antibody is an indispensable tool for researchers and scientists working in the fields of cell biology, cancer research, and developmental biology. Its reliable performance and accurate detection capabilities make it an ideal choice for investigating the role of centriolin in various cellular processes and disease mechanisms.

Order the Centriolin Polyclonal Antibody today and unlock new insights into the intricate world of centriolin biology. Trust in its exceptional quality and performance to advance your research and contribute to the scientific community's understanding of this crucial protein.