Cdk7 Polyclonal Antibody

Cyclin dependent kinase 7 encoded by CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.

The Cdk7 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cdk7 protein expression in various biological samples. This antibody has been extensively validated and exhibits exceptional sensitivity and specificity, ensuring accurate and reproducible results.

Cdk7, also known as cyclin-dependent kinase 7, plays a crucial role in cell cycle regulation and transcriptional regulation. It is a key component of the Cdk-activating kinase (CAK) complex, which phosphorylates and activates cyclin-dependent kinases (Cdks) involved in cell cycle progression. Additionally, Cdk7 is involved in the regulation of transcription by phosphorylating the C-terminal domain (CTD) of RNA polymerase II.

The Cdk7 Polyclonal Antibody has been produced using high-quality immunogens and advanced immunization techniques, resulting in a highly specific antibody with minimal cross-reactivity. It has been rigorously tested and validated for various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its exceptional sensitivity and specificity, this antibody enables accurate detection and quantification of Cdk7 protein expression in a wide range of samples, including cell lysates, tissue extracts, and cultured cells. Its versatility and reliability make it an ideal tool for researchers studying cell cycle regulation, transcriptional regulation, and related fields.

In summary, the Cdk7 Polyclonal Antibody is a valuable research tool that offers high specificity, sensitivity, and reliability for the detection and analysis of Cdk7 protein expression. Its exceptional performance and versatility make it an essential component of any laboratory involved in cell cycle and transcriptional regulation research.