Cdk5 Polyclonal Antibody

CDK5 encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the cyclin dependent kinase 5 encoded by CDK5 does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-8. Alternative splicing results in multiple transcript variants.

The Cdk5 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cyclin-dependent kinase 5 (Cdk5) protein. This antibody has been extensively validated for its exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

Cdk5 is a crucial member of the cyclin-dependent kinase family, playing a pivotal role in regulating cell cycle progression, neuronal development, and synaptic plasticity. Dysregulation of Cdk5 has been implicated in numerous pathological conditions, such as neurodegenerative diseases, cancer, and mental disorders. Therefore, the accurate detection and quantification of Cdk5 protein expression levels are of utmost importance in both basic research and clinical studies.

The Cdk5 Polyclonal Antibody exhibits high specificity towards Cdk5, ensuring minimal cross-reactivity with other related proteins. It has been rigorously tested and validated using various cell lines and tissue samples, guaranteeing reliable and reproducible results. This antibody demonstrates exceptional sensitivity, enabling the detection of even low-abundance Cdk5 protein levels.

Furthermore, the Cdk5 Polyclonal Antibody is produced using state-of-the-art techniques, ensuring high purity and batch-to-batch consistency. It is supplied as a liquid formulation, ready for immediate use without the need for any additional preparation. The antibody is provided in a convenient size, allowing for multiple experiments and minimizing wastage.

In summary, the Cdk5 Polyclonal Antibody is a superior research tool that offers exceptional specificity, sensitivity, and reliability for the detection and analysis of Cdk5 protein. Its high-quality formulation and extensive validation make it an ideal choice for researchers and scientists working in the fields of cell biology, neuroscience, and cancer research.