Cdk2 Polyclonal Antibody

CDK2 encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. Cyclin dependent kinase 2 is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.

The Cdk2 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cyclin-dependent kinase 2 (Cdk2) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdk2 protein. The antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Cdk2 Polyclonal Antibody is a valuable tool for researchers studying cell cycle regulation and cancer biology. Cdk2 is a key regulator of the cell cycle and is involved in the transition from G1 to S phase. Dysregulation of Cdk2 activity has been implicated in the development and progression of various types of cancer. The Cdk2 Polyclonal Antibody can be used to investigate the expression and activity of Cdk2 in cancer cells and tissues, as well as in normal cells.

This antibody has been extensively validated for specificity and sensitivity, ensuring reliable and reproducible results. It has been shown to detect endogenous levels of Cdk2 in various cell lines and tissues, and has minimal cross-reactivity with other proteins. The Cdk2 Polyclonal Antibody is supplied in a liquid form and can be stored at -20°C for long-term use.

In summary, the Cdk2 Polyclonal Antibody is a high-quality antibody that provides reliable and specific detection of Cdk2 in various biological samples. It is a valuable tool for researchers studying cell cycle regulation and cancer biology, and is suitable for use in a range of applications.