Cdk1/Cdc2 Polyclonal Antibody

Cyclin dependent kinase 1 encoded by CDK1 is a member of the Ser/Thr protein kinase family. Cyclin dependent kinase 1 is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this CDK1.

The Cdk1/Cdc2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cdk1/Cdc2 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and specificity towards the target protein.

Cdk1/Cdc2, also known as cyclin-dependent kinase 1 or cell division control protein 2, plays a crucial role in cell cycle regulation and progression. It is involved in the transition from G2 phase to mitosis, where it phosphorylates a wide range of substrates to initiate mitotic events. Dysregulation of Cdk1/Cdc2 activity has been implicated in various diseases, including cancer.

The Cdk1/Cdc2 Polyclonal Antibody has been extensively validated for its performance in immunoblotting, immunohistochemistry, and immunofluorescence applications. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of Cdk1/Cdc2 protein expression in both normal and pathological tissues.

This antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising its quality. The Cdk1/Cdc2 Polyclonal Antibody is compatible with a wide range of detection systems and can be used in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence assays.

In summary, the Cdk1/Cdc2 Polyclonal Antibody is a valuable tool for researchers studying cell cycle regulation and its implications in disease. Its high specificity, sensitivity, and versatility make it an ideal choice for reliable and accurate detection of Cdk1/Cdc2 protein expression in diverse biological samples.