CdcA3 Polyclonal Antibody

Cell cycle events are regulated by the sequential activation and deactivation of cyclin dependent kinases (Cdks) and by the proteolysis of cyclins. The cell division control (Cdc) genes are required at various points in the cell cycle. CdcA3 (Cell division cycle-associated protein 3), also known as TOME1 (Trigger of mitotic entry protein 1) and GRCC8 (Gene-rich cluster protein C8), is a 268 amino acid cytoplasmic protein that is required for entry into mitosis. By participating with E3 ligase complexes, CdcA3 is involved in ubiquination and degradation of the mitosis-inhibitory kinase Wee 1, leading to the dephosphorylation of Cdc2 in the late G2 phase. CdcA3 itself is targeted for destruction by anaphase promoting complex (APC) in the G1 phase of the cell cycle, then allowing for Wee 1 accumulation during interphase.

The CdcA3 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CdcA3 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques, ensuring its exceptional sensitivity and specificity.

The CdcA3 Polyclonal Antibody exhibits a strong affinity towards the CdcA3 protein, making it an ideal choice for a wide range of applications, including western blotting, immunohistochemistry, and immunofluorescence. Its exceptional performance in these techniques allows for accurate and precise quantification of CdcA3 protein levels in different experimental settings.

This antibody is produced using high-quality materials and undergoes rigorous quality control measures to ensure batch-to-batch consistency and reliability. Its superior specificity and minimal cross-reactivity with other proteins make it an invaluable tool for researchers studying cell division and related processes.

The CdcA3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is available in various sizes to accommodate different experimental needs. Each vial is carefully packaged to maintain its stability and integrity during shipping and storage.

In summary, the CdcA3 Polyclonal Antibody is a highly specific and reliable tool that enables accurate detection and analysis of CdcA3 protein expression. Its exceptional performance, superior specificity, and ease of use make it an essential component for researchers in the field of cell biology and related disciplines.