Cdc42EP5 Polyclonal Antibody

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts.

The Cdc42EP5 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cdc42EP5 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdc42EP5 protein. The antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. The Cdc42EP5 Polyclonal Antibody has been validated for its specificity and sensitivity, ensuring reliable and accurate results. This antibody is an essential tool for researchers studying the role of Cdc42EP5 protein in various cellular processes and diseases.