Cdc37 Polyclonal Antibody

Cell division cycle 37 encoded by CDC37 is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

The Cdc37 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cdc37 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Cdc37 protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and is suitable for use in a variety of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

The Cdc37 protein is a molecular chaperone that plays a critical role in the folding and maturation of a wide range of client proteins, including many kinases and transcription factors. Dysregulation of Cdc37 expression or function has been implicated in a variety of diseases, including cancer, neurodegenerative disorders, and cardiovascular disease. The Cdc37 Polyclonal Antibody provides a valuable tool for researchers studying the role of Cdc37 in these and other disease processes.

This antibody has been extensively validated for specificity and sensitivity, and has been shown to detect endogenous Cdc37 protein in a variety of cell types and tissues. It is supplied as a liquid in phosphate-buffered saline (PBS) containing 0.02% sodium azide as a preservative. The Cdc37 Polyclonal Antibody is available in a range of sizes to meet the needs of different research applications. With its high specificity and sensitivity, this antibody is an essential tool for researchers studying the role of Cdc37 in cellular processes and disease.