Cdc16 Polyclonal Antibody

Cell division cycle 16 encoded by CDC16 functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified.

The Cdc16 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Cdc16 protein expression in various biological samples. This antibody has been extensively validated for its exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) applications.

The Cdc16 Polyclonal Antibody exhibits a high affinity towards the Cdc16 protein, a crucial component of the anaphase-promoting complex/cyclosome (APC/C). This protein plays a pivotal role in regulating cell cycle progression and ensuring accurate chromosome segregation during mitosis. By targeting Cdc16, this antibody enables researchers to investigate the intricate mechanisms underlying cell division and its dysregulation in various pathological conditions.

With its exceptional sensitivity and specificity, the Cdc16 Polyclonal Antibody offers researchers a valuable tool for studying the expression patterns and subcellular localization of Cdc16 in different tissues and cell types. Its robust performance ensures reliable and reproducible results, facilitating accurate data interpretation and analysis.

The Cdc16 Polyclonal Antibody is manufactured using state-of-the-art techniques and undergoes rigorous quality control procedures to ensure optimal performance and consistency. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation steps.

In summary, the Cdc16 Polyclonal Antibody is a highly reliable and specific tool for investigating the expression and localization of Cdc16 protein in various biological samples. Its exceptional performance in IHC, IF, and WB applications, coupled with its ease of use, makes it an indispensable asset for researchers studying cell cycle regulation and related processes.