CD95 Polyclonal Antibody

Fas cell surface death receptor encoded by FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. Several alternatively spliced transcript variants have been described, some of which are candidates for nonsense-mediated mRNA decay (NMD). The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform.

The Cdc34 Polyclonal Antibody is a highly reliable and efficient tool for the detection and analysis of Cdc34 protein expression. This antibody has been meticulously developed and rigorously tested to ensure its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence.

With its exceptional affinity and selectivity, the Cdc34 Polyclonal Antibody exhibits minimal cross-reactivity with other proteins, enabling accurate and precise results. It recognizes the conserved epitope of Cdc34, a crucial component of the ubiquitin-proteasome system involved in cell cycle regulation and protein degradation.

This antibody is produced using state-of-the-art techniques, ensuring batch-to-batch consistency and high purity. Its superior performance guarantees reliable and reproducible results, making it an indispensable tool for researchers and scientists studying cell biology, cancer research, and protein degradation pathways.

The Cdc34 Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into various experimental protocols. Its exceptional quality and performance make it an ideal choice for both basic research and clinical applications.

Order your Cdc34 Polyclonal Antibody today and unlock new insights into the intricate mechanisms of cell cycle regulation and protein degradation. Experience the reliability and accuracy that this antibody offers, and accelerate your scientific discoveries.