CD73 Polyclonal Antibody

5'-nucleotidase ecto encoded by NT5E is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

The CD73 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of CD73 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CD73 protein. The antibody has been purified using protein A affinity chromatography and is suitable for use in various applications, including Western blotting, immunohistochemistry, and flow cytometry.

The CD73 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in detecting CD73 protein in various human tissues and cell lines. It has been shown to recognize both the full-length and truncated forms of CD73 protein, making it a versatile tool for studying the expression and function of CD73 in different biological contexts.

This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the CD73 Polyclonal Antibody is a reliable and high-quality tool for the detection of CD73 protein in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying the role of CD73 in various physiological and pathological processes.