CD53 Polyclonal Antibody

CD53 molecule encoded by CD53 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.

The CD53 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD53 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring high affinity and specificity towards CD53.

CD53, also known as Cluster of Differentiation 53, is a transmembrane glycoprotein that belongs to the tetraspanin family. It is widely expressed on the surface of various cell types, including leukocytes, platelets, and endothelial cells. CD53 plays a crucial role in cell adhesion, signal transduction, and immune response regulation.

The CD53 Polyclonal Antibody exhibits exceptional sensitivity and selectivity, making it an ideal choice for a wide range of applications, including immunohistochemistry, western blotting, flow cytometry, and immunofluorescence. It enables researchers to accurately detect and quantify CD53 expression levels in different tissues and cell types.

This antibody is supplied as a liquid formulation, allowing for easy handling and convenient storage. It has been extensively validated for its performance and reliability, ensuring consistent and reproducible results. The CD53 Polyclonal Antibody is compatible with various experimental conditions and can be used in both research and clinical settings.

In summary, the CD53 Polyclonal Antibody is a valuable tool for investigating the role of CD53 in cellular processes and disease pathogenesis. Its high specificity, sensitivity, and versatility make it an essential component of any immunological research project.