CD45 Polyclonal Antibody

The protein encoded by PTPRC (protein tyrosine phosphatase, receptor type C) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of PTPRC, which encode distinct isoforms, have been reported.

The CD45 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD45 protein expression in various biological samples. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reproducibility.

The CD45 Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for a wide range of applications, including immunohistochemistry, flow cytometry, and western blotting. It recognizes the CD45 antigen, a transmembrane protein that is widely expressed on all nucleated hematopoietic cells.

With its superior performance characteristics, this antibody enables accurate and precise identification and quantification of CD45-positive cells in complex biological systems. It offers excellent signal-to-noise ratio, minimal background interference, and high signal intensity, allowing for reliable and reproducible results.

The CD45 Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming and error-prone antibody preparation. It is provided in a convenient format, ensuring ease of use and compatibility with various experimental protocols.

In summary, the CD45 Polyclonal Antibody is a highly reliable and specific tool for the detection and analysis of CD45 protein expression. Its exceptional performance characteristics, ease of use, and compatibility with multiple applications make it an indispensable asset for researchers in the field of immunology and hematopoietic studies.