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SKU:BT-AP01505

CD44 Polyclonal Antibody

CD44 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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The protein encoded by CD44 (CD44 molecule (Indian blood group)) is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid  (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases  (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for CD44 undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

The CD44 Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of CD44 protein expression in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and consistency in every batch.

CD44 is a cell surface glycoprotein that plays a crucial role in cell adhesion, migration, and signaling. It is involved in numerous physiological and pathological processes, including embryogenesis, inflammation, and cancer metastasis. The CD44 Polyclonal Antibody recognizes the extracellular domain of CD44, allowing for the precise identification and characterization of CD44-positive cells.

This antibody has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and flow cytometry. It exhibits exceptional sensitivity and specificity, enabling accurate and reliable detection of CD44 expression levels. The CD44 Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue sections, and cultured cells.

With its superior performance and versatility, the CD44 Polyclonal Antibody is an indispensable tool for researchers and clinicians studying CD44 biology and its implications in disease progression. Its robust and reproducible results make it an ideal choice for both basic research and clinical applications.

To ensure optimal performance, the CD44 Polyclonal Antibody should be stored at -20°C upon arrival. It is supplied in a convenient and ready-to-use format, eliminating the need for time-consuming preparation. Each vial contains sufficient antibody for multiple experiments, providing excellent value for money.

In summary, the CD44 Polyclonal Antibody is a reliable and efficient tool for the detection and analysis of CD44 protein expression. Its high specificity, sensitivity, and versatility make it an essential component of any research or diagnostic laboratory.

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