CD44 Polyclonal Antibody

CD44 molecule encoded by CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for CD44 undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

The CD44 polyclonal antibody is a highly specific and reliable tool designed for the detection and analysis of CD44 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards CD44 antigen. With its exceptional performance, this antibody enables accurate identification and characterization of CD44, a cell surface glycoprotein involved in numerous physiological and pathological processes.

The CD44 polyclonal antibody exhibits exceptional versatility, making it suitable for a wide range of applications, including immunohistochemistry, immunofluorescence, western blotting, and flow cytometry. Its robust performance allows for precise and reproducible results, facilitating comprehensive investigations into the role and function of CD44 in various research areas, such as cancer biology, immunology, and stem cell research.

This antibody is meticulously validated to ensure its specificity and reliability. It has been extensively tested against a variety of cell lines and tissues, demonstrating its exceptional performance in detecting CD44 expression. Furthermore, this antibody exhibits minimal cross-reactivity with other related antigens, ensuring accurate and specific detection of CD44 protein.

The CD44 polyclonal antibody is supplied in a convenient and ready-to-use format, allowing for immediate application in laboratory experiments. It is provided in a liquid formulation, ensuring ease of use and eliminating the need for time-consuming reconstitution steps. Additionally, this antibody is available in various sizes to accommodate different experimental requirements.

In summary, the CD44 polyclonal antibody is a highly specific and reliable tool for the detection and analysis of CD44 protein expression. With its exceptional performance, versatility, and meticulous validation, this antibody is an invaluable asset for researchers aiming to unravel the complexities of CD44 biology and its implications in various physiological and pathological processes.