CD42d Polyclonal Antibody

Human platelet glycoprotein V (GP5) is a part of the Ib-V-IX system of surface glycoproteins that constitute the receptor for von Willebrand factor (VWF; MIM 613160) and mediate the adhesion of platelets to injured vascular surfaces in the arterial circulation, a critical initiating event in hemostasis. The main portion of the receptor is a heterodimer composed of 2 polypeptide chains, an alpha chain (GP1BA; MIM 606672) and a beta chain (GP1BB; MIM 138720), that are linked by disulfide bonds. The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX (GP9; MIM 173515) and GP5. Mutations in GP1BA, GP1BB, and GP9 have been shown to cause Bernard-Soulier syndrome (MIM 231200), a bleeding disorder (review by Lopez et al. 1998 [PubMed: 9616133]).

The CD6 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD6 protein expression in various biological samples. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards CD6 antigen.

The CD6 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including immunohistochemistry, immunofluorescence, and western blotting. It enables researchers to investigate the distribution and localization of CD6 protein in tissues and cells, facilitating a comprehensive understanding of its biological functions.

With its superior specificity, the CD6 Polyclonal Antibody guarantees minimal cross-reactivity with other proteins, ensuring accurate and reliable results. Its high sensitivity allows for the detection of low levels of CD6 protein expression, making it an ideal choice for studies requiring precise quantification.

This antibody is manufactured using advanced techniques and undergoes stringent quality control measures to ensure batch-to-batch consistency and reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming and complex preparation steps.

The CD6 Polyclonal Antibody is compatible with a variety of sample types, including formalin-fixed paraffin-embedded tissues, frozen sections, and cultured cells. Its versatility and ease of use make it an indispensable tool for researchers in the fields of immunology, oncology, and cell biology.

In summary, the CD6 Polyclonal Antibody is a reliable and highly specific reagent that enables accurate detection and analysis of CD6 protein expression. Its exceptional performance, ease of use, and compatibility with various applications and sample types make it an invaluable asset for researchers seeking to unravel the complexities of CD6 biology.