CD298 Polyclonal Antibody

ATPase Na+/K+ transporting subunit beta 3 encoded by ATP1B3 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. ATP1B3 encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for ATP1B3, and it is located on chromosome 2.

The CD298 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CD298 protein expression in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CD298 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CD298 protein, making it an ideal tool for various research applications.

The CD298 Polyclonal Antibody is suitable for use in a variety of immunological techniques, including Western blotting, immunohistochemistry, and immunofluorescence. It has been validated for use in human, mouse, and rat samples, and has been shown to detect CD298 protein expression in a variety of tissues and cell types.

This antibody is supplied as a purified IgG fraction, and has been extensively characterized for its specificity and sensitivity. It is provided in a convenient format, with a recommended working dilution range of 1:1000 to 1:5000 for Western blotting, and 1:50 to 1:200 for immunohistochemistry and immunofluorescence.

Overall, the CD298 Polyclonal Antibody is a reliable and high-quality reagent that is ideal for researchers studying CD298 protein expression in various biological samples. Its high specificity and sensitivity make it an essential tool for understanding the role of CD298 in various physiological and pathological processes.