CD1E Polyclonal Antibody

CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined.

The CD1e Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and analysis of CD1e protein expression in various biological samples. This antibody is produced through a rigorous process of immunization using a purified recombinant CD1e protein, ensuring high affinity and specificity towards the target antigen.

The CD1e Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and flow cytometry. It enables researchers to investigate the expression patterns and cellular localization of CD1e protein in different tissues and cell types, facilitating a deeper understanding of its biological functions and potential implications in various diseases.

With its superior sensitivity and specificity, this antibody offers reliable and reproducible results, making it an invaluable tool for both basic research and clinical studies. Its versatility allows for the examination of CD1e protein expression in diverse experimental settings, enabling researchers to unravel its role in antigen presentation, lipid metabolism, and immune responses.

The CD1e Polyclonal Antibody is manufactured under strict quality control standards, ensuring consistent performance and batch-to-batch reproducibility. It is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. Additionally, it exhibits excellent stability, enabling long-term storage without compromising its performance.

In summary, the CD1e Polyclonal Antibody is a reliable and versatile tool for the detection and analysis of CD1e protein expression. Its high specificity, sensitivity, and ease of use make it an essential component in various research areas, including immunology, cell biology, and disease pathology.