CD179b Polyclonal Antibody

The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. IGLL1 does not undergo rearrangement. Mutations in IGLL1 can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for IGLL1.

The CD179b Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CD179b protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CD179b protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CD179b protein, making it an ideal tool for various research applications.

The CD179b Polyclonal Antibody is suitable for use in a variety of immunoassays, including Western blotting, immunohistochemistry, and flow cytometry. It has been validated for use in human, mouse, and rat samples, and has been shown to exhibit minimal cross-reactivity with other proteins. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

The CD179b Polyclonal Antibody is a valuable tool for researchers studying the role of CD179b protein in various biological processes, including immune cell activation, inflammation, and cancer. Its high sensitivity and specificity make it an ideal reagent for detecting and quantifying CD179b protein in complex biological samples. With its reliable performance and ease of use, the CD179b Polyclonal Antibody is an essential tool for any researcher working in the field of immunology.