CD177 Polyclonal Antibody

CD177 encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

The CD177 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced using high-quality materials and advanced techniques to ensure optimal performance and reliability. It is a polyclonal antibody that targets the CD177 protein, which is expressed on the surface of neutrophils and plays a crucial role in neutrophil activation and migration. The CD177 Polyclonal Antibody is suitable for use in various techniques, including Western blotting, immunohistochemistry, and flow cytometry. It has been extensively validated for its specificity and sensitivity, making it an ideal tool for researchers studying neutrophil biology and related diseases. This antibody is available in various sizes and formats to meet the diverse needs of researchers. With its exceptional performance and reliability, the CD177 Polyclonal Antibody is an excellent choice for any research project requiring a high-quality antibody targeting the CD177 protein.