CD158e Polyclonal Antibody

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

The CD158e Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD158e protein expression. This antibody is produced using advanced techniques and rigorous quality control measures to ensure optimal performance and reproducibility.

The CD158e Polyclonal Antibody exhibits exceptional sensitivity and specificity, making it an ideal choice for various applications, including immunohistochemistry, immunofluorescence, and western blotting. It recognizes the CD158e protein with high affinity, enabling accurate and precise quantification of its expression levels in various biological samples.

This antibody is manufactured using high-quality materials and undergoes stringent purification processes to eliminate any potential contaminants, ensuring maximum purity and reliability. It has been extensively validated in multiple experimental settings, demonstrating consistent and robust results.

The CD158e Polyclonal Antibody is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows. It is provided in a liquid formulation, eliminating the need for reconstitution and minimizing the risk of sample contamination.

With its exceptional performance characteristics and reliable results, the CD158e Polyclonal Antibody is an indispensable tool for researchers and scientists studying CD158e protein expression and its role in various biological processes.