CD158b2/j Polyclonal Antibody

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response.

The CD158b2/j Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CD158b2/j protein expression. This antibody is produced through a rigorous process, ensuring its high affinity and sensitivity towards the target protein.

The CD158b2/j Polyclonal Antibody exhibits exceptional performance in various applications, including immunohistochemistry, immunofluorescence, and western blotting. Its versatility allows for the accurate identification and localization of CD158b2/j protein in a wide range of samples, enabling researchers to gain valuable insights into its biological functions and roles.

With its superior quality and performance, the CD158b2/j Polyclonal Antibody guarantees reproducible and consistent results, making it an indispensable tool for scientific investigations and biomedical research. Its robustness and reliability make it suitable for use in both academic and industrial settings.

Furthermore, the CD158b2/j Polyclonal Antibody is manufactured under strict quality control measures, ensuring batch-to-batch consistency and minimizing any potential variability. It is supplied in a convenient and ready-to-use format, allowing for immediate application without the need for additional preparation.

In summary, the CD158b2/j Polyclonal Antibody is a highly specific, reliable, and versatile tool that facilitates the accurate detection and analysis of CD158b2/j protein expression. Its exceptional performance, reproducibility, and convenience make it an essential component for researchers and scientists engaged in the study of CD158b2/j and its associated biological processes.