CD137L Polyclonal Antibody

The protein (tumor necrosis factor superfamily member 9) encoded by TNFSF9 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.

The CD137L Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of CD137L protein expression in various biological samples. This antibody is produced using advanced recombinant technology, ensuring high purity and quality.

CD137L, also known as 4-1BBL, is a member of the tumor necrosis factor (TNF) superfamily and plays a crucial role in immune regulation and activation. It is primarily expressed on antigen-presenting cells, such as dendritic cells and macrophages, and can interact with its receptor CD137 (4-1BB) on T cells, leading to T cell activation and proliferation.

The CD137L Polyclonal Antibody exhibits excellent specificity and sensitivity, enabling accurate detection and quantification of CD137L protein levels in various experimental settings, including Western blotting, immunohistochemistry, and flow cytometry. It has been extensively validated and proven to provide reliable and reproducible results.

This antibody is supplied as a liquid formulation, allowing for easy handling and storage. It is provided in a convenient size, ensuring cost-effectiveness and minimizing waste. The CD137L Polyclonal Antibody is suitable for both research and diagnostic applications, making it an indispensable tool for scientists and clinicians studying immune responses and developing novel therapeutic strategies.

In summary, the CD137L Polyclonal Antibody is a highly reliable and versatile reagent that enables accurate detection and analysis of CD137L protein expression. Its exceptional specificity, sensitivity, and ease of use make it an essential tool for researchers and clinicians in the field of immunology.