CCK-AR Polyclonal Antibody

CCKAR (cholecystokinin A receptor) encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones. This receptor is a major physiologic mediator of pancreatic enzyme secretion and smooth muscle contraction of the gallbladder and stomach. In the central and peripheral nervous system this receptor regulates satiety and the release of beta-endorphin and dopamine.

The CCK-AR Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Cholecystokinin A receptor (CCK-AR) in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CCK-AR protein. The resulting polyclonal antibody has been purified using protein A affinity chromatography and validated for its specificity and sensitivity through various assays.

The CCK-AR Polyclonal Antibody is suitable for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to detect CCK-AR in human, mouse, and rat tissues, making it a versatile tool for researchers studying the role of CCK-AR in various physiological and pathological processes.

This antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is recommended to store the antibody at -20°C for long-term storage and to avoid repeated freeze-thaw cycles.

In summary, the CCK-AR Polyclonal Antibody is a reliable and high-quality tool for the detection of CCK-AR in various biological samples. Its specificity and sensitivity make it an ideal choice for researchers studying the role of CCK-AR in various physiological and pathological processes.