CCDC45 Polyclonal Antibody

The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC45 (coiled-coil domain containing 45) is a 821 amino acid protein encoded by a gene that maps to human chromosome 17q23.3. Chromosome 17 comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and
BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

The CCK-BR Polyclonal Antibody is a highly specific and sensitive immunological tool designed for the detection and quantification of Cholecystokinin B receptor (CCK-BR) protein. This antibody is produced using advanced techniques, ensuring its high affinity and specificity towards the target protein.

The CCK-BR Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to explore the expression and localization of CCK-BR in different tissues and cell types with utmost precision and accuracy.

With its superior sensitivity, this antibody allows for the detection of even low levels of CCK-BR protein, making it an invaluable tool for studying the role of CCK-BR in various physiological and pathological processes. Its reliable and reproducible results ensure the generation of robust data, facilitating further investigations and scientific advancements.

The CCK-BR Polyclonal Antibody is manufactured under stringent quality control measures, guaranteeing its consistent performance and reliability. It is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory.

Choose the CCK-BR Polyclonal Antibody for your research needs and unlock new insights into the intricate mechanisms involving Cholecystokinin B receptor. Trust in its exceptional quality and performance to drive your scientific discoveries forward.