CCDC4 Polyclonal Antibody

BEND4 (BEN domain-containing protein 4) is a 530 amino acid protein that contains a BEN domain. BEND4 exists as five alternatively spiced isoforms and is considered a complete proteome. BEN domain mediates protein–DNA and protein–protein interactions during chromatin organization and transcription. BEN domain may play a role in organization of viral DNA during replication or transcription. The BEND4 gene maps to human chromosome 4p13. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer.

The CCDC4 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CCDC4 protein expression in various biological samples. This antibody has been meticulously developed using advanced immunization techniques and exhibits exceptional sensitivity and specificity.

The CCDC4 Polyclonal Antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the CCDC4 protein. The resulting antibody is purified using a combination of affinity chromatography and protein A/G purification methods, ensuring a high level of purity and minimal cross-reactivity.

This antibody has been extensively validated for its performance in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically recognize the CCDC4 protein in a wide range of species, including human, mouse, and rat.

The CCDC4 Polyclonal Antibody offers numerous advantages over other antibodies on the market. Its high specificity and sensitivity enable accurate and reliable detection of CCDC4 protein expression, even at low levels. Additionally, its versatility allows for its use in a variety of experimental settings, making it an ideal choice for researchers in the fields of molecular biology, cell biology, and cancer research.

In summary, the CCDC4 Polyclonal Antibody is a superior tool for the detection and analysis of CCDC4 protein expression. Its exceptional specificity, sensitivity, and versatility make it an invaluable asset for researchers seeking to unravel the complexities of CCDC4 function in various biological processes.