CCDC102B Polyclonal Antibody

CCDC102B (coiled-coil domain containing 102B), also known as AN, ACY1L or HsT1731, is a 513 amino acid protein that exists as three alternatively spliced isoforms. Widely expressed and found in multiple CNV (copy-number variant) regions, CCDC102B contains the deletion breakpoint of a maternally inherited deletion, which is 2.7 Mb in size, and maps to human chromosome 18q22.1. CCDC102B may play a role in the pathogenesis of diaphragmatic hernia, microphthalmia, colorectal carcinoma and schizophrenia. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Translocation between chromosomes 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18.

The CCDC102B Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of CCDC102B protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human CCDC102B protein. The resulting polyclonal antibody exhibits high affinity and specificity towards CCDC102B protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The CCDC102B Polyclonal Antibody is purified using a combination of protein A and protein G affinity chromatography, ensuring high purity and minimal cross-reactivity with other proteins. This antibody is supplied as a liquid formulation in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. The CCDC102B Polyclonal Antibody is suitable for use in a wide range of research applications, including cancer research, developmental biology, and neuroscience.

In summary, the CCDC102B Polyclonal Antibody is a reliable and high-quality immunological reagent that offers exceptional sensitivity and specificity for the detection and quantification of CCDC102B protein in various biological samples. Its high purity and minimal cross-reactivity make it an ideal tool for a wide range of research applications.