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SKU:BT-AP01236

Cathepsin B Polyclonal Antibody

Cathepsin B Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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CTSB encodes a member of the C1 family of peptidases. Alternative splicing of CTSB results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein (cathepsin B) has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of CTSB have been identified.

The Cathepsin B Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cathepsin B protein in various biological samples. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards Cathepsin B.

Cathepsin B is a lysosomal cysteine protease that plays a crucial role in various physiological and pathological processes, including protein degradation, antigen presentation, and tumor invasion. The Cathepsin B Polyclonal Antibody recognizes the active form of Cathepsin B, enabling accurate and reliable measurement of its expression levels.

This antibody has been extensively validated in multiple applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent performance in terms of sensitivity, specificity, and reproducibility, making it an ideal choice for both research and diagnostic purposes.

The Cathepsin B Polyclonal Antibody is supplied as a liquid formulation, ready to use for immediate application. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage. The antibody is stable and long-lasting, allowing for multiple experiments without compromising its performance.

With its exceptional quality and reliability, the Cathepsin B Polyclonal Antibody is an indispensable tool for researchers and clinicians studying Cathepsin B-related processes and diseases. Its accurate and precise detection capabilities make it an invaluable asset in the field of proteomics and biomedical research.

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