Cathepsin B Polyclonal Antibody

CTSB encodes a member of the C1 family of peptidases. Alternative splicing of CTSB results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the cathepsin B light and heavy chains, which can dimerize to form the double chain form of the enzyme. This enzyme is a lysosomal cysteine protease with both endopeptidase and exopeptidase activity that may play a role in protein turnover. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer's disease, the most common cause of dementia. Overexpression of the encoded protein (cathepsin B) has been associated with esophageal adenocarcinoma and other tumors. Multiple pseudogenes of CTSB have been identified.

The Cathepsin B Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Cathepsin B protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards Cathepsin B.

Cathepsin B is a lysosomal cysteine protease that plays a crucial role in various physiological and pathological processes, including protein degradation, antigen presentation, and tumor invasion. The Cathepsin B Polyclonal Antibody recognizes the active form of Cathepsin B, enabling accurate measurement of its enzymatic activity.

This antibody has been extensively validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits excellent performance in both human and animal samples, making it a versatile tool for researchers in diverse fields.

The Cathepsin B Polyclonal Antibody is supplied as a liquid formulation, allowing for easy and convenient handling. It is provided in a range of sizes to suit different experimental needs. Each batch of antibody undergoes rigorous quality control tests to ensure consistent and reliable results.

With its exceptional sensitivity and specificity, the Cathepsin B Polyclonal Antibody is an indispensable tool for studying the role of Cathepsin B in various biological processes. Its high-quality performance and ease of use make it an ideal choice for researchers seeking accurate and reproducible results.