Catenin-Beta1 Polyclonal Antibody

The protein (catenin beta 1) encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.

The Catenin-Beta1 Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of Catenin-Beta1 protein in various biological samples. This antibody is produced using high-quality polyclonal antibodies that have been purified and validated for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Catenin-Beta1 Polyclonal Antibody is a valuable tool for researchers studying the role of Catenin-Beta1 in various cellular processes, including cell adhesion, migration, and signaling. This antibody has been extensively tested and validated for its specificity and sensitivity, ensuring accurate and reliable results in a variety of experimental settings.

With its high-quality production and rigorous validation process, the Catenin-Beta1 Polyclonal Antibody is an essential tool for researchers seeking to understand the complex mechanisms underlying cellular processes and disease pathogenesis. Its versatility and reliability make it an ideal choice for a wide range of applications in the fields of molecular biology, biochemistry, and cell biology.