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SKU:BT-AP01203

Caspase-3 Polyclonal Antibody

Caspase-3 Polyclonal Antibody

Regular price $275.00 USD
Regular price Sale price $275.00 USD
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CASP3 encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein (caspase 3) cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

The Caspase 3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Caspase 3 protein in various biological samples. This antibody is produced using advanced immunization techniques, ensuring high affinity and specificity towards the target protein.

Caspase 3, also known as cysteine-aspartic acid protease 3, plays a crucial role in the execution phase of apoptosis, a programmed cell death process. It is involved in the cleavage of various cellular substrates, leading to the dismantling of the cell and its eventual demise. Therefore, the accurate measurement of Caspase 3 levels is essential for understanding the apoptotic pathway and its dysregulation in various diseases.

The Caspase 3 Polyclonal Antibody exhibits exceptional performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both the proenzyme and the active form of Caspase 3, enabling the detection of the protein at different stages of apoptosis. This antibody demonstrates minimal cross-reactivity with other caspase family members, ensuring reliable and specific results.

With its high sensitivity and specificity, the Caspase 3 Polyclonal Antibody is an invaluable tool for researchers and clinicians studying apoptosis and its implications in various pathological conditions. Its superior performance and consistent results make it an ideal choice for a wide range of experimental and diagnostic applications.

Order the Caspase 3 Polyclonal Antibody today and unlock new insights into the intricate mechanisms of apoptosis, paving the way for advancements in disease research and therapeutic interventions.

The Caspase-3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Caspase-3 protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Caspase-3, also known as cysteine-aspartic acid protease 3, is a crucial enzyme involved in the execution phase of apoptosis, a programmed cell death process. It plays a pivotal role in the cleavage of various cellular substrates, leading to cell death. Therefore, the accurate measurement of Caspase-3 protein levels is essential for studying apoptosis-related processes and diseases.

The Caspase-3 Polyclonal Antibody exhibits exceptional specificity towards Caspase-3, with minimal cross-reactivity to other caspase family members. It has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence. This antibody demonstrates excellent sensitivity, enabling the detection of low levels of Caspase-3 protein in samples.

Furthermore, the Caspase-3 Polyclonal Antibody is supplied in a ready-to-use format, eliminating the need for time-consuming and error-prone antibody preparation steps. It is compatible with a wide range of sample types, including cell lysates, tissue homogenates, and purified protein samples. The antibody is provided in a convenient storage format, ensuring long-term stability and ease of use.

In summary, the Caspase-3 Polyclonal Antibody is a reliable and efficient tool for the accurate detection and quantification of Caspase-3 protein. Its high specificity, sensitivity, and ease of use make it an ideal choice for researchers and scientists studying apoptosis-related processes and diseases.

The Caspase-3 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Caspase-3 protein in various biological samples. This antibody is produced using advanced recombinant DNA technology, ensuring high purity and batch-to-batch consistency.

Caspase-3 is a crucial enzyme involved in the execution phase of apoptosis, playing a pivotal role in programmed cell death. The Caspase-3 Polyclonal Antibody recognizes the active form of Caspase-3, enabling precise and reliable analysis of apoptotic processes in diverse research areas, including cancer biology, neurodegenerative diseases, and immunology.

This antibody exhibits exceptional sensitivity and specificity, allowing for accurate detection of Caspase-3 even at low concentrations. It has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence, ensuring reliable and reproducible results.

The Caspase-3 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without compromising performance. The antibody is optimized for use in a wide range of species, including human, mouse, and rat, making it a versatile tool for researchers across different fields.

With its superior quality and performance, the Caspase-3 Polyclonal Antibody is an indispensable tool for scientists seeking to unravel the intricate mechanisms of apoptosis and its implications in various physiological and pathological processes. Trust in this antibody to deliver accurate and reproducible results, enabling groundbreaking discoveries in the field of cell biology and beyond.

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