Caldesmon Polyclonal Antibody

CALD1 (caldesmon 1) encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of CALD1 results in multiple transcript variants encoding distinct isoforms.

The Caldesmon Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect and quantify the expression of caldesmon protein in various biological samples. This antibody has been produced using high-quality polyclonal antibodies that have been purified and validated to ensure optimal performance in a range of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The Caldesmon Polyclonal Antibody is a valuable tool for researchers studying the role of caldesmon in various physiological and pathological processes, including smooth muscle contraction, cell migration, and cancer progression. This antibody has been extensively tested and validated to ensure high specificity and sensitivity, enabling accurate and reliable detection of caldesmon protein in a variety of sample types.

The Caldesmon Polyclonal Antibody is supplied in a convenient and easy-to-use format, making it ideal for use in a range of research applications. With its high specificity, sensitivity, and reliability, this antibody is an essential tool for researchers studying the function and regulation of caldesmon in various biological systems.