Caldesmon Polyclonal Antibody

CALD1 (caldesmon 1) encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

The Caldesmon Polyclonal Antibody is a highly specific and sensitive antibody that has been developed for the detection of caldesmon protein in various biological samples. This antibody has been produced using high-quality polyclonal antibodies that have been purified and characterized to ensure optimal performance and specificity. The Caldesmon Polyclonal Antibody is suitable for use in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for its ability to detect caldesmon protein in various tissues and cell types, making it an ideal tool for researchers studying the role of caldesmon in various physiological and pathological processes. The Caldesmon Polyclonal Antibody is available in various sizes and formats to meet the specific needs of different research applications. It is a reliable and effective tool for the detection of caldesmon protein and is an essential component of any research project focused on this important protein.