Calbindin D28K Polyclonal Antibody

Calbindin encoded by CALB1 is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease.

The Calbindin D28K Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of Calbindin D28K protein in various biological samples. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards the target protein.

Calbindin D28K is a calcium-binding protein that plays a crucial role in calcium homeostasis and neuronal function. It is predominantly expressed in the central nervous system, particularly in the cerebellum and hippocampus. The Calbindin D28K Polyclonal Antibody recognizes and binds to the epitopes of Calbindin D28K, enabling accurate and reliable detection of this protein in tissue sections, cell lysates, and other biological samples.

This antibody exhibits exceptional sensitivity, allowing for the detection of even low levels of Calbindin D28K protein. It is suitable for various applications, including immunohistochemistry, western blotting, and immunofluorescence. The Calbindin D28K Polyclonal Antibody provides reliable and reproducible results, making it an ideal choice for researchers and scientists working in the fields of neuroscience, neurobiology, and calcium signaling.

With its high specificity and sensitivity, this antibody offers a valuable tool for studying the role of Calbindin D28K in various physiological and pathological processes. Its robust performance and consistent results make it an indispensable asset for both basic research and clinical investigations.

The Calbindin D28K Polyclonal Antibody is supplied in a convenient and ready-to-use format, ensuring ease of use and saving valuable time in the laboratory. It is produced under stringent quality control measures to guarantee batch-to-batch consistency and optimal performance.

In summary, the Calbindin D28K Polyclonal Antibody is a reliable and efficient tool for the detection and quantification of Calbindin D28K protein. Its high specificity, sensitivity, and versatility make it an essential component of any research project or diagnostic assay involving the study of Calbindin D28K.