CAGE-1 Polyclonal Antibody

CAGE (cancer-associated gene protein), also known as DEAD box protien 53 (DDX53) or DEAD box protein CAGE, belongs to the DEAD box helicase family. It contains one helicase ATP-binding domain, one helicase C-terminal domain and one KH domain. CAGE localizes to the nucleus and, in normal adult tissues, is exclusively expressed in testis but it has also been found in a wide variety of cancer tissues and cell lines. Overexpression of CAGE leads to the activation of FAK, ERK and p38 MAPK along with a reduction in reactive oxygen species (ROS). It is also responsible for inducing catalase activity and therefore enhancing cell motility. This suggests that CAGE may enhance the migration of cancer cells. In addition, hypomethylation of the CAGE promoter region is associated with tumor progression and may serve as a valuable marker in cancer diagnosis.

The CAGE-1 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of CAGE-1 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and accuracy.

The CAGE-1 Polyclonal Antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its exceptional specificity enables precise identification and quantification of CAGE-1 protein, facilitating comprehensive research in diverse fields such as cancer biology, developmental biology, and molecular genetics.

This antibody is produced through a rigorous purification process, resulting in a high-quality product with minimal background noise. Its polyclonal nature allows for enhanced sensitivity and broad reactivity, ensuring reliable and reproducible results across various experimental conditions.

The CAGE-1 Polyclonal Antibody is supplied in a convenient and user-friendly format, making it suitable for both experienced researchers and newcomers in the field. Its long shelf life and stability guarantee consistent performance, eliminating the need for frequent antibody replacements.

Choose the CAGE-1 Polyclonal Antibody for its exceptional specificity, sensitivity, and reliability, and unlock new insights into the intricate mechanisms of CAGE-1 protein function. Experience the utmost confidence in your research with this cutting-edge tool that promises to revolutionize your scientific endeavors.