Brp16 Polyclonal Antibody

Brp16 is a 256 amino acid protein encoded by a gene on human chromosome 8. Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

The Brp16 Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of the Brp16 protein. The Brp16 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in Western blotting, immunohistochemistry, and immunofluorescence assays.

The Brp16 protein is a member of the Brp family of proteins, which are involved in the regulation of gene expression and cellular differentiation. The Brp16 Polyclonal Antibody recognizes the Brp16 protein specifically and does not cross-react with other members of the Brp family or other proteins.

The Brp16 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified using a protein A column. This antibody is provided in a liquid form and can be used directly in various research applications without any additional purification steps.

Overall, the Brp16 Polyclonal Antibody is a reliable and high-quality tool for researchers studying the Brp16 protein and its role in cellular processes. Its specificity and sensitivity make it an ideal choice for a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence assays.