BinCARD Polyclonal Antibody

BinCARD (Bcl10-interacting CARD protein) is a 228 amino acid protein that exists as two alternatively spiced isoforms. BinCARD localizes to nucleus and is expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart, liver, thymus and brain. Containing a CARD domain, BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner. The BinCARD gene maps to chromosome 9q22.1. Chromosome 9 consists of about 145 million bases and 4% of the human genome and encodes nearly 900 genes. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKAP.

The BinCARD Polyclonal Antibody is a highly specialized and meticulously crafted product designed to cater to the needs of researchers and scientists in the field of immunology. This antibody is derived from a diverse pool of B cells, ensuring a broad spectrum of reactivity and specificity. With its exceptional sensitivity and accuracy, the BinCARD Polyclonal Antibody offers an invaluable tool for the detection and quantification of various antigens in a wide range of biological samples.

The BinCARD Polyclonal Antibody boasts an impressive affinity for its target antigens, enabling precise and reliable results in immunohistochemistry, immunofluorescence, and Western blotting applications. Its exceptional performance is attributed to the rigorous purification process, which guarantees minimal cross-reactivity and background noise. This antibody is meticulously validated to ensure consistent and reproducible results, making it an indispensable asset for any laboratory or research facility.

Furthermore, the BinCARD Polyclonal Antibody is manufactured using cutting-edge technology and adheres to the highest quality standards. Each batch undergoes stringent quality control measures to ensure batch-to-batch consistency and reliability. The antibody is supplied in a convenient and user-friendly format, allowing for easy storage and handling.

In summary, the BinCARD Polyclonal Antibody is a superior product that offers unparalleled sensitivity, specificity, and reliability. Its exceptional performance, combined with its ease of use and stringent quality control measures, make it an indispensable tool for researchers and scientists in the field of immunology. Invest in the BinCARD Polyclonal Antibody today and unlock new possibilities in your research endeavors.