ACE1 Polyclonal Antibody

ACE encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

The ACE1 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of ACE1 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human ACE1 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards ACE1 protein, making it an ideal tool for various applications in research and diagnostics.

The ACE1 Polyclonal Antibody is suitable for use in various immunoassays, including Western blotting, immunohistochemistry, and ELISA. It has been validated for use in human, mouse, and rat samples, and has been shown to detect ACE1 protein in a variety of tissues and cell types. This antibody is supplied as a purified IgG fraction, and has been tested for purity and specificity to ensure consistent and reliable results.

In summary, the ACE1 Polyclonal Antibody is a high-quality immunological reagent that offers exceptional sensitivity and specificity for the detection and quantification of ACE1 protein in various biological samples. Its versatility and reliability make it an essential tool for researchers and clinicians working in the fields of cardiovascular disease, hypertension, and renal function.