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ELK Biotechnology
SKU:ES11980
LDHB Rabbit Polyclonal Antibody
LDHB Rabbit Polyclonal Antibody
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$248.00 USD
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LDHB Rabbit Polyclonal Antibody
Overview
| Product name: | LDHB rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein. AA range 65-105 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 36kD |
| GeneID(Human): | 3945 |
| Human Swiss-Prot No: | P07195 |
| Cellular localization: | Cytoplasm. Mitochondrion inner membrane ; Peripheral membrane protein . |
| Background: | This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016], |
| Species Reactivity: | Human;Rat;Mouse |
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