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ELK Biotechnology

SKU:ES11980

LDHB Rabbit Polyclonal Antibody

LDHB Rabbit Polyclonal Antibody

Regular price $248.00 USD
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LDHB Rabbit Polyclonal Antibody

Overview

Product name: LDHB rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein. AA range 65-105
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 36kD
GeneID(Human): 3945
Human Swiss-Prot No: P07195
Cellular localization: Cytoplasm. Mitochondrion inner membrane ; Peripheral membrane protein .
Background: This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13. [provided by RefSeq, Feb 2016],
Species Reactivity: Human;Rat;Mouse
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