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ELK Biotechnology
SKU:ES11896
DNMT1 Rabbit Polyclonal Antibody
DNMT1 Rabbit Polyclonal Antibody
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$248.00 USD
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DNMT1 Rabbit Polyclonal Antibody
Overview
| Product name: | DNMT1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 177kD |
| GeneID（Human）: | 1786 |
| Human Swiss-Prot No: | P26358 |
| Cellular localization: | Nucleus . |
| Background: | This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016], |
| Species Reactivity: | Human;Mouse;Rat |
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