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ELK Biotechnology

SKU:ES11878

HNF1A Rabbit Polyclonal Antibody

HNF1A Rabbit Polyclonal Antibody

Regular price $248.00 USD
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HNF1A Rabbit Polyclonal Antibody

Overview

Product name: HNF1A rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 69kD
GeneID(Human): 6927
Human Swiss-Prot No: P20823
Cellular localization: Nucleus .
Background: The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
Species Reactivity: Human;Mouse;Rat
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