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ELK Biotechnology
SKU:ES11793
ABCA1 Rabbit Polyclonal Antibody
ABCA1 Rabbit Polyclonal Antibody
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$248.00 USD
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ABCA1 Rabbit Polyclonal Antibody
Overview
| Product name: | ABCA1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein AA range: 1112-1180 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 248kD |
| GeneID（Human）: | 19 |
| Human Swiss-Prot No: | O95477 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . Endosome . |
| Background: | The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Golden hamster |
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