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ELK Biotechnology
SKU:ES11774
BRD2 Rabbit Polyclonal Antibody
BRD2 Rabbit Polyclonal Antibody
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$248.00 USD
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BRD2 Rabbit Polyclonal Antibody
Overview
| Product name: | BRD2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein AA range: 300-350 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 88kD |
| GeneID（Human）: | 6046 |
| Human Swiss-Prot No: | P25440 |
| Cellular localization: | Nucleus . Detected on chromatin and nucleosomes. |
| Background: | This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Rat;Mouse; |
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