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ELK Biotechnology

SKU:ES11768

URP2 Rabbit Polyclonal Antibody

URP2 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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URP2 Rabbit Polyclonal Antibody

Overview

Product name: URP2 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein AA range: 52-102
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 73kD
GeneID(Human): 83706
Human Swiss-Prot No: Q86UX7
Cellular localization: Cell projection, podosome . Present in the F-actin surrounding ring structure of podosomes, which are specialized adhesion structures of hematopoietic cells. .
Background: Kindlins are a small family of proteins that mediate protein-protein interactions involved in integrin activation and thereby have a role in cell adhesion, migration, differentiation, and proliferation. The protein encoded by this gene has a key role in the regulation of hemostasis and thrombosis. This protein may also help maintain the membrane skeleton of erythrocytes. Mutations in this gene cause the autosomal recessive leukocyte adhesion deficiency syndrome-III (LAD-III). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2010],
Species Reactivity: Human;Rat;Mouse;
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