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ELK Biotechnology
SKU:ES11622
P2RY6 Rabbit Polyclonal Antibody
P2RY6 Rabbit Polyclonal Antibody
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$248.00 USD
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P2RY6 Rabbit Polyclonal Antibody
Overview
| Product name: | P2RY6 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 180-260 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 36kD |
| GeneID(Human): | 5031 |
| Human Swiss-Prot No: | Q15077 |
| Cellular localization: | Cell membrane; Multi-pass membrane protein. |
| Background: | The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Mar 2013], |
| Species Reactivity: | Human;Rat;Mouse |
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