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ELK Biotechnology
SKU:ES11467
GP161 Rabbit Polyclonal Antibody
GP161 Rabbit Polyclonal Antibody
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$248.00 USD
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GP161 Rabbit Polyclonal Antibody
Overview
| Product name: | GP161 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 180-260 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 58kD |
| GeneID（Human）: | 23432 |
| Human Swiss-Prot No: | Q8N6U8 |
| Cellular localization: | Cell projection, cilium membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . Mainly localizes to primary cilium in a TULP3 and IFT-A complex-dependent manner. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes and is apparently not degraded (By similarity). . |
| Background: | Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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