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ELK Biotechnology
SKU:ES11437
DHX58 Rabbit Polyclonal Antibody
DHX58 Rabbit Polyclonal Antibody
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$248.00 USD
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DHX58 Rabbit Polyclonal Antibody
Overview
| Product name: | DHX58 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 451-500 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 74kD |
| GeneID（Human）: | 79132 |
| Human Swiss-Prot No: | Q96C10 |
| Cellular localization: | Cytoplasm . |
| Background: | function:Negative regulator of host innate immune defense against viruses. The repressor domain of DHX58 interacts with DDX58 and negatively regulates DDX58-mediated signaling. Binds dsRNA produced during viral replication, in particuliar HCV RNA.,similarity:Belongs to the helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with DDX58 and probably blocks its homomultimerization., |
| Species Reactivity: | Human;Mouse |
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